Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001420) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DARPin anti-Abeta D23
|
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| Synonyms |
DARPin D23
|
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| Molecular Weight | 12 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS027 | [1] | ||||
| Scaffold Name | DARPin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Inhibitor | Alzheimer disease [ICD-11: 8A20] | Kd: 159 nM | University of Zurich | [1] | |