Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001348) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Monobody anti-MLKL clone 26
|
|||||
| Synonyms |
Monobody MLKL_26
|
|||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | HT-29 cells | |||||
| Selection Method | Phage display and yeast display | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS047 | [1] | ||||
| Scaffold Name | Monobody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Mixed lineage kinase domain-like protein | Binder | Tools for inducing necroptotic cell death | Kd: 176 nM | Walter and Eliza Hall Institute of Medical Research | [1] | |