General Information of Synthetic Binding Protein (SBP) (ID: SBP001291)
SBP Name
Monobody anti-B7.1 CFN13
Synonyms
Monobody CFN13
Molecular Weight 13.7? kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS047
Scaffold Info
[1]
Scaffold Name Monobody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
T-lymphocyte activation antigen CD80
BTS Info
Inhibitor Research tool N.A. Tianjin University [1]
References
1 Construction of small molecular CTLA4 analogs with CD80-binding affinity. Biochem Biophys Res Commun. 2019 Jun 4;513(3):694-700.