Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP001290) | ||||||
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SBP Name |
Monobody anti-EphA2 E10
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Synonyms |
Monobody E10
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Molecular Weight | 12.6 kDa | |||||
Thermal Denaturation TEMP | 82 ℃ | |||||
Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Expression System | Escherichia coli BL21 (DE3) | |||||
Selection Method | Yeast display | |||||
Highest Status | Research | |||||
Sequence Length | 113 | |||||
SBP Sequence |
>Monobody anti-EphA2 E10
VSDVPRDLEVVAATPTSLLISWYYPFCAFYYRITYGETGGNSPVQEFTVRYYRITYGETG GNSPVQEFTVPRSYKAPSATISGLKPGVDYTITVYAATCLGSYSRPISINYRT |
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3D Structure | ||||||
Computationally Modelled Structure | ||||||
Click to Save PDB File | ||||||
Template Name | Fibronectin type III domain (FN3) | |||||
Protein Scaffold Information of This SBP | ||||||
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Scaffold ID | PS047 | [1] | ||||
Scaffold Name | Monobody | |||||
Scaffold Class | Non-Antibody | |||||
Fold Type | Beta-Sheets + Loops | |||||
Binding Target(s) of This SBP (BTS) |
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BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
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Ephrin type-A receptor 2 | Binder | Cancers [ICD-11: 2D4Z] | Kd: 2.1 nM | Chonnam National University Medical School | [1] | |