Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001259) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Monobody anti-SHP2-SH2 aCS3
|
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| Synonyms |
Monobody aCS3
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS047 | [1] | ||||
| Scaffold Name | Monobody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Src-homology 2 domain-containing phosphatase 2 | Inhibitor | Research tool | Kd: 4 nM | Medical Research Council Protein Phosphorylation and Ubiquitylation Unit | [1] | |