General Information of Synthetic Binding Protein (SBP) (ID: SBP001176)
SBP Name
Monobody anti-Bpe S8
Synonyms
Monobody S8
Molecular Weight 10.4 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
PDB ID 6BQO
Sequence Length 95
SBP Sequence
>Monobody anti-Bpe S8
SSVPTKLEVVAATPTSLLISWDAPAVTVDHYVITYGETGAYWSYQEFTVPGSKSTATISG
LKPGVDYTITVYANPYSDAPIYYSYHSPISINYRT
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS047
Scaffold Info
[1]
Scaffold Name Monobody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fluc channel homologue Bpe
BTS Info
Blocker Research tool Kd: 200000 nM University of Michigan [1]
References
1 Cork-in-Bottle Occlusion of Fluoride Ion Channels by Crystallization Chaperones. Structure. 2018 Apr 3;26(4):635-639.e1.