Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001057) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Nanobody anti-CD72 clone B5
|
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| Synonyms |
NbB5
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | CAR+ T cells | |||||
| Selection Method | Yeast display | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS048 | [1] | ||||
| Scaffold Name | Nanobody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| B-cell differentiation antigen CD72 | Binder | B-cell malignancies [ICD-11: 2A86.0] | Kd: 1 nM | University of California | [1] | |