Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00228) | ||||||
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| BTS Name |
B-cell differentiation antigen CD72
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| Synonyms |
Lyb-2; CD antigen CD72
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| BTS Type |
Protein
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| Gene Name |
CD72
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| Organism |
Homo sapiens (Human)
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| Function |
Plays a role in B-cell proliferation and differentiation.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MAEAITYADLRFVKAPLKKSISSRLGQDPGADDDGEITYENVQVPAVLGVPSSLASSVLG
DKAAVKSEQPTASWRAVTSPAVGRILPCRTTCLRYLLLGLLLTCLLLGVTAICLGVRYLQ VSQQLQQTNRVLEVTNSSLRQQLRLKITQLGQSAEDLQGSRRELAQSQEALQVEQRAHQA AEGQLQACQADRQKTKETLQSEEQQRRALEQKLSNMENRLKPFFTCGSADTCCPSGWIMH QKSCFYISLTSKNWQESQKQCETLSSKLATFSEIYPQSHSYYFLNSLLPNGGSGNSYWTG LSSNKDWKLTDDTQRTRTYAQSSKCNKVHKTWSWWTLESESCRSSLPYICEMTAFRFPD |
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| Sequence Length |
359
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Nanobody anti-CD72 clone B5 | Research | Binder | Kd: 1 nM | B-cell malignancies [ICD-11: 2A86.0] | [1] | |