Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000865) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Defensin A-based binder anti-TNF-alpha
|
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| Synonyms |
TNF-binding peptide
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Template Name | Insect defensin A | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS029 | [1] | ||||
| Scaffold Name | Defensin A-based binder | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | One Alpha-Helix + Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor | Binder | Tools as conformation-constrained peptide | N.A. | Beijing Institute of Basic Medical Sciences | [1] | |