General Information of Synthetic Binding Protein (SBP) (ID: SBP000852)
SBP Name
TEM1-beta-lactamase based binder anti-mAbs P19L3-01
Synonyms
TEM1-beta-lactamase based binder P19L3-01
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Selection Method Phage display
Highest Status Research
Template Name FdBla
Protein Scaffold Information of This SBP
Scaffold ID PS061
Scaffold Info
[1]
Scaffold Name TEM1-beta-lactamase based binder
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Monoclonal antibodies
BTS Info
Binder Research tool Kd: 7.6 nM Catholic University of Leuven [1]
References
1 Engineering a regulatable enzyme for homogeneous immunoassays. Nat Biotechnol. 1999 Jan;17(1):67-72.