Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000789)
SBP Name	Zinc finger domain anti-DNA variants
Synonyms	Anti-DNA zinc finger variants
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method	Phage display
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS068 Scaffold Info					[1] , [2]
Scaffold Name	Zinc finger domain
Scaffold Class	Non-Antibody
Fold Type	Alpha-Helices + Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
DNA	BTS Info	Binder	Research tool	N.A.	Genetic Regulatory Center; Massachusetts General Hospital	[1] , [2]

References

1	Structure-based DNA-binding prediction and design. Methods Mol Biol. 2010;649:77-88.
2	An improved strategy for constructing "designer" Cys2His2 zinc finger proteins. Discov Med. 2003 Dec;3(19):32-5.