Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000786) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Designed TPR protein anti-Keap1 Charge Nrf2 CTPR2
|
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| Synonyms |
Designed TPR protein Charge Nrf2 CTPR2
|
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| Molecular Weight | 11.5 kDa | |||||
| Thermal Denaturation TEMP | 65.6 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>Loop sequence
DPDNLDEETGEFLDPDN |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS030 | [1] | ||||
| Scaffold Name | Designed TPR protein | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Beta-Turns | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Kelch-like ECH-associated protein 1 | Binder | Research tool | Kd: 817 nM | University of Cambridge | [1] | |