General Information of Synthetic Binding Protein (SBP) (ID: SBP000782)
SBP Name
Designed TPR protein anti-Dss1 T-Mod(Dss1A)
Synonyms
Designed TPR protein T-Mod(Dss1A)
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Template Name TPR2A domain
Protein Scaffold Information of This SBP
Scaffold ID PS030
Scaffold Info
[1]
Scaffold Name Designed TPR protein
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Turns
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Exoribonuclease II, mitochondrial
BTS Info
Binder Research tool Kd: 20200 nM Yale University [1]
References
1 Designed proteins to modulate cellular networks. ACS Chem Biol. 2010 Jun 18;5(6):545-52.