General Information of Synthetic Binding Protein (SBP) (ID: SBP000781)
SBP Name
Designed TPR protein anti-PTIEEVD clone TPR1C7
Synonyms
Designed TPR protein peptide TPR1C7
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Highest Status Research
Template Name TPR1 domain
Protein Scaffold Information of This SBP
Scaffold ID PS030
Scaffold Info
[1]
Scaffold Name Designed TPR protein
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Turns
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
PTIEEVD peptide
BTS Info
Binder Research tool Kd: 70000 nM Yale University [1]
References
1 Creating novel proteins by combining design and selection. Protein Eng Des Sel. 2010 Jun;23(6):449-55.