Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000778) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Designed TPR protein anti-hsp90 CTPR390+
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| Synonyms |
Designed TPR protein CTPR390+
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>First A helix
AEAWKNLGNAYYK >Second A helix ASAWYNLGNAYYK >Third A helix AKAWYRRGNAYYK >First B helix KYQKAIKYYQKALKL >Second B helix KYQKAIKYYQKALKL >Third B helix KYQKAIKYYQKALKL |
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| Template Name | CTPR3 | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS030 | [1] | ||||
| Scaffold Name | Designed TPR protein | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Beta-Turns | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Heat shock protein HSP 90-beta | Binder | Cancers [ICD-11: 2D4Z] | Kd: 1000 nM | Yale University | [1] | |