Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP000701) | ||||||
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SBP Name |
VNAR anti-EphA2 mmE1
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Synonyms |
VNAR mmE1
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Molecular Weight | 12.0 kDa | |||||
Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Expression System | Escherichia coli MBH 71-18 | |||||
Selection Method | Yeast display | |||||
Highest Status | Research | |||||
Sequence Length | 110 | |||||
SBP Sequence |
>VNAR anti-EphA2 mmE1
MAARLEQTLTTTTKEAGESLTINCVLKGSVYGLGRTYWYFTKKGATKKASLSTGGRYSDT KNTASKSFSLRISDLRIEDSGTYHCEAKAYSYADPLFIMIEGGGTLLTVK |
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3D Structure | ||||||
Computationally Modelled Structure | ||||||
Click to Save PDB File | ||||||
Protein Scaffold Information of This SBP | ||||||
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Scaffold ID | PS065 | [1] | ||||
Scaffold Name | vNAR | |||||
Scaffold Class | Antibody fragment | |||||
Fold Type | Beta-Sheets + Loops | |||||
Binding Target(s) of This SBP (BTS) |
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BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
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Ephrin type-A receptor 2 | Binder | Research tool | Kd: 368 nM | Technical University of Darmstadt | [1] | |