General Information of Synthetic Binding Protein (SBP) (ID: SBP000680)
SBP Name
scFv anti-VP40 DSTL095
Synonyms
scFv DSTL095
Molecular Weight 28.4 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Bacteria
Selection Method Phage display
Highest Status Research
Sequence Length 270
SBP Sequence
>scFv anti-VP40 DSTL095
MKYLLPTAAAGLLLLAAQPAMADYKDIGLTQSPLTLSVTIGQPASISCKSSQSLLDSDGK
TYLNWLLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISRVEAEDLGVYYCWQ
GTHFPQTFGGGTKLELKRGGGGSGGGGSGGGGSGGGGSEVMLVESGGGLAKPGGSLKLSC
AASGFTFSRYGMAWVRQNPEKRLEWVATISGGGSHTYYPDSVKGRFTISRDNAKNNLYLE
MSSLRSEDTALYYCTRADYWGQGTTLTVSS
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Matrix protein VP40
BTS Info
Binder Tools for detecting Ebolavirus infection N.A. Defence Science and Technology Laboratory [1]
References
1 Isolation and characterisation of Ebolavirus-specific recombinant antibody fragments from murine and shark immune libraries. Mol Immunol. 2011 Sep;48(15-16):2027-37.