General Information of Synthetic Binding Protein (SBP) (ID: SBP000679)
SBP Name
scFv anti-VP40 DSTL094
Synonyms
scFv DSTL094
Molecular Weight 27.9 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Bacteria
Selection Method Phage display
Highest Status Research
Sequence Length 260
SBP Sequence
>scFv anti-VP40 DSTL094
MKYLLPTAAAGLLLLAAQPAMADYKDIVMTQTPLTLSVTIGQPASISCKSSQSLLDSDGK
TYLNWLLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISRVEAEDLGVYYCWQ
GTHFPQTFGGGTKLELKRGGGGSGGGGSEVMLVESGGDLVKPGGSLKLSCAASGFTFSKY
GMAWVRQTPDKRLEWVATISSGGSYTYYPDSVKGRFTISRDDAMNTLYLQMSSLKSEDTA
MYYCTRADYWGQGTTLTVSS
3D Structure
Computationally Modelled Structure
Click to Save PDB File
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Matrix protein VP40
BTS Info
Binder Tools for detecting Ebolavirus infection N.A. Defence Science and Technology Laboratory [1]
References
1 Isolation and characterisation of Ebolavirus-specific recombinant antibody fragments from murine and shark immune libraries. Mol Immunol. 2011 Sep;48(15-16):2027-37.