General Information of Synthetic Binding Protein (SBP) (ID: SBP000650)
SBP Name
Affitin anti-ERBB1 B10
Synonyms
Affitin B10
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Ribosome display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS007
Scaffold Info
[1]
Scaffold Name Affitin
Scaffold Class Non-Antibody
Fold Type One Alpha-Helix + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Epidermal growth factor receptor
BTS Info
Binder Imaging agent Kd: 27.6 nM Free University of Brussels [1]
Epidermal growth factor receptor
BTS Info
Binder Imaging agent Kd: 83 nM Free University of Brussels [1]
References
1 Nanofitin as a New Molecular-Imaging Agent for the Diagnosis of Epidermal Growth Factor Receptor Over-Expressing Tumors. Bioconjug Chem. 2017 Sep 20;28(9):2361-2371.