General Information of Synthetic Binding Protein (SBP) (ID: SBP000596)
SBP Name
Evibody anti-Integrin RGD-7B
Synonyms
Evibody RGD-7B
Molecular Weight 15 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
SBP Sequence
>CDR3
FLPRGDDYPRR
Template Name CTLA-4
Protein Scaffold Information of This SBP
Scaffold ID PS033
Scaffold Info
[1]
Scaffold Name Evibody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Integrin alpha-v-beta-3
BTS Info
Binder Research tool N.A. Target Quest [1]
References
1 Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands. FEBS Lett. 2000 Jun 23;475(3):225-31.