General Information of Synthetic Binding Protein (SBP) (ID: SBP000581)
SBP Name
Beta-Hairpin mimetic anti-LptD/BamA JB-95
Synonyms
Beta-Hairpin mimetic JB-95
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 14
SBP Sequence
>Beta-Hairpin mimetic anti-LptD/BamA JB-95
PWRIRI[d-Arg]WKRLRR[d-Pro]
Sequence Description The first Pro and the last dPro are linked.
Protein Scaffold Information of This SBP
Scaffold ID PS016
Scaffold Info
[1]
Scaffold Name Beta-Hairpin mimetic
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Beta-Turn
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Outer membrane protein assembly factor BamA
BTS Info
Binder Tools for molecular recognition N.A. University of Zurich [1]
LPS-assembly protein LptD
BTS Info
Binder Tools for molecular recognition N.A. University of Zurich [1]
References
1 Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines. Acc Chem Res. 2017 Jun 20;50(6):1323-1331.