General Information of Synthetic Binding Protein (SBP) (ID: SBP000578)
SBP Name
Beta-Hairpin mimetic anti-LptD L27-11
Synonyms
Beta-Hairpin mimetic L27-11
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 14
SBP Sequence
>Beta-Hairpin mimetic anti-LptD L27-11
PTWLKKRRWKKAK[d-Pro]
Sequence Description The first Pro and the last dPro are linked.
Protein Scaffold Information of This SBP
Scaffold ID PS016
Scaffold Info
[1]
Scaffold Name Beta-Hairpin mimetic
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Beta-Turn
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
LPS-assembly protein LptD
BTS Info
Binder Pseudomonas infection [ICD-11: XN022] N.A. University of Zurich [1]
References
1 Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines. Acc Chem Res. 2017 Jun 20;50(6):1323-1331.