Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP000544) | ||||||
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SBP Name |
Knottin anti-c-Mpl AGTP-3
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Synonyms |
Knottin AGTP-3
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Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Expression System | Escherichia coli | |||||
Highest Status | Research | |||||
Template Name | AgRP | |||||
Template Sequence Description | Cys I and Cys IV form disulfide bonds; Cys II and Cys V form disulfide bonds; Cys III and Cys VIII form disulfide bonds; Cys VI and Cys VII form disulfide bonds. | |||||
Protein Scaffold Information of This SBP | ||||||
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Scaffold ID | PS042 | [1] | ||||
Scaffold Name | Knottin | |||||
Scaffold Class | Non-Antibody | |||||
Fold Type | Beta-Sheets + Loops | |||||
Binding Target(s) of This SBP (BTS) |
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BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
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Thrombopoietin receptor | Antagonist | Research tool | N.A. | University of Jena Medical School | [1] | |