General Information of Synthetic Binding Protein (SBP) (ID: SBP000516)
SBP Name
Affibody anti-PDGFRbeta Z09591
Synonyms
Affibody Z09591
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS004
Scaffold Info
[1]
Scaffold Name Affibody
Scaffold Class Non-Antibody
Fold Type Three Alpha-Helices
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Platelet-derived growth factor receptor beta
BTS Info
Binder Imaging agent N.A. Uppsala University [1]
References
1 Imaging of platelet-derived growth factor receptor expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591. J Nucl Med. 2014 Feb;55(2):294-300.