General Information of Synthetic Binding Protein (SBP) (ID: SBP000475)
SBP Name
Affibody anti-ERBB1 Z(EGFR:1907)
Synonyms
Affibody Z(EGFR: 1907)
Molecular Weight 7 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS004
Scaffold Info
[1]
Scaffold Name Affibody
Scaffold Class Non-Antibody
Fold Type Three Alpha-Helices
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Epidermal growth factor receptor
BTS Info
Binder Imaging agent for patients with cancer Kd: 5.4 nM Harbin Medical University [1]
References
1 Analysis of Progress and Challenges of EGFR-Targeted Molecular Imaging in Cancer With a Focus on Affibody Molecules. Mol Imaging. Jan-Dec 2019;18:1536012118823473.