Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000474) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Affibody anti-ERBB1 Z(EGFR:955)
|
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| Synonyms |
Affibody Z(EGFR: 955)
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| Molecular Weight | 7 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Template Name | IgG-binding B-domain of staphylococcal protein A analog Z | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS004 | [1] | ||||
| Scaffold Name | Affibody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Three Alpha-Helices | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | Binder | Imaging agent for patients with cancer | Kd: 130-185 nM | Harbin Medical University | [1] | |