Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000433) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Fynomer anti-BACE2 2B-H11
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| Synonyms |
Fynomer 2B-H11
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| Molecular Weight | 9.5 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli TG1 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| PDB ID | 3ZL7 | |||||
| Sequence Length | 82 | |||||
| SBP Sequence |
>Fynomer anti-BACE2 2B-H11
MRGSGVTLFVALYDYEARPNRPLDLSFHKGEKFQILNWWHVRGDWWEARSLTTGETGYIP SNYVAPVDSIQGEQKLISEEDL |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | Fyn SH3 | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS035 | [1] | ||||
| Scaffold Name | Fynomer | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Beta-secretase 2 | Binder | Tools as crystallization helpers | Kd: 6.2 nM | Roche Ltd | [1] | |