General Information of Synthetic Binding Protein (SBP) (ID: SBP000405)
SBP Name
Repebody anti-IgG-Fc D10
Synonyms
Repebody D10
Molecular Weight 29.8 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Sequence Length 266
SBP Sequence
>Repebody anti-IgG-Fc D10
ETITVSTPIKQIFPDDAFAETIKANLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQ
YLPNVRYLALGGNKLHDISALKELTNLTYLELKWNQLQSLPNGVFDKLTNLKELVLNSNQ
LQSLPDGVFDKLTNLTYLNLAHNQLQSLPKGVFDKLTNLTFLELEMNQLQSLPEGVFDKL
TQLKDLRLYQNQLKSVPDGVFDRLTSLQYIWLHDNPWDCTCPGIRYLSEWINKHSGVVRN
SAGSVAPDSAKCSGSGKPVRSIICPT
3D Structure
Computationally Modelled Structure
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Template Name Repebody
Protein Scaffold Information of This SBP
Scaffold ID PS055
Scaffold Info
[1]
Scaffold Name Repebody
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fc fragment of human immunoglobulin G
BTS Info
Binder Research tool Kd: 300 nM Korea Advanced Institute of Science and Technology (KAIST) [1]
References
1 Protein binder for affinity purification of human immunoglobulin antibodies. Anal Chem. 2014 Jun 17;86(12):6019-25.