Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000383) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
OBody anti-HEWL AM2EP06
|
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| Synonyms |
OBody AM2EP06
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| Molecular Weight | 11.8 kDa | |||||
| Thermal Denaturation TEMP | 79.2 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli DH5 (alpha) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| PDB ID | 4GN4 | |||||
| Sequence Length | 108 | |||||
| SBP Sequence |
>OBody anti-HEWL AM2EP06
AVYPKKTHWTAEITPNLHGSEVVVAGWVAHLGDYGRVKIVKVSDREGGAAVPVYLERGKT PDHLFKVFAELSREDVVVIKGIVEASEQYGSATGVEIFPSEIWILNKA |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | OBody NL8 | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS050 | [1] | ||||
| Scaffold Name | OBody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Hen egg-white lysozyme | Inhibitor | Tools for molecular recognition | Kd: 250 nM | University of Waikato; OBodies Limited | [1] | |