General Information of Synthetic Binding Protein (SBP) (ID: SBP000360)
SBP Name
Affimer anti-VEGFR-2 A9
Synonyms
Affimer A9
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS006
Scaffold Info
[1]
Scaffold Name Affimer
Scaffold Class Non-Antibody
Fold Type One Alpha-Helix + Beta-Sheets+ Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Vascular endothelial growth factor receptor 2
BTS Info
Inhibitor Tools for modulators of protein function;tools for affinity histochemistry Kd: 41 nM University of Leeds [1]
References
1 Affimer proteins are versatile and renewable affinity reagents. Elife. 2017 Jun 27;6:e24903.