Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000289) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-uPA mupain-1-16
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| Synonyms |
Macrocyclic peptide mupain-1-16
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| PDB ID | 4X1N | |||||
| Sequence Length | 10 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-uPA mupain-1-16
CPAYS[L-3-(N-Amidino-4-piperidyl)alanine]-YLDC |
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| Sequence Description | Cys I and Cys II form disulfide bonds. | |||||
| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | Mupain-1 | |||||
| Template Sequence Description | Cys I and Cys II form disulfide bonds. | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Urokinase-type plasminogen activator | Inhibitor | Research tool | Kd: 840 nM | Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences | [1] | |