Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000266) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Bicyclic peptide anti-PKK PK100
|
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| Synonyms |
Bicyclic peptide PK100
|
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| Molecular Weight | 1.2 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Mammalian cells | |||||
| Highest Status | Research | |||||
| Sequence Length | 11 | |||||
| SBP Sequence |
>Bicyclic peptide anti-PKK PK100
ACFKACRVNCA |
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| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS017 | [1] | ||||
| Scaffold Name | Bicyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Plasma kallikrein | Inhibitor | Hereditary angioedema [ICD-11: 4A00.14] | N.A. | Lausanne Federal Institute of Technology | [1] | |