General Information of Synthetic Binding Protein (SBP) (ID: SBP000257)
SBP Name
Bicyclic peptide anti-Rab GTPase clone?25
Synonyms
Bicyclic peptide?25
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 17
SBP Sequence
>Bicyclic peptide anti-Rab GTPase clone?25
DDEX1EQFX2YHLX3SFNX4V
Protein Scaffold Information of This SBP
Scaffold ID PS017
Scaffold Info
[1]
Scaffold Name Bicyclic peptide
Scaffold Class Non-Antibody
Fold Type Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Rab GTPase
BTS Info
Activator Tools for the modulation of challenging protein targets Kd: 6600 nM Max-Planck-Institute of Molecular Physiology [1]
References
1 Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides. Nat Commun. 2016 Apr 14;7:11300.