Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000250) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DARPin anti-ERK2 pEM1
|
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| Synonyms |
DARPin pEM1
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | FLI-TRAP | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS027 | [1] | ||||
| Scaffold Name | DARPin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 | Binder | Tools for recognizing post-translationally phosphorylated proteins | Kd: 87.1 nM | Cornell University | [1] | |
| Mitogen-activated protein kinase 1 | Binder | Tools for recognizing post-translationally phosphorylated proteins | Kd: >3500 nM | Cornell University | [1] | |