General Information of Synthetic Binding Protein (SBP) (ID: SBP000243)
SBP Name
Affilin anti-FN 77405
Synonyms
Affilin 77405
Molecular Weight 17.5 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli NovaBlue (DE3)
Selection Method Phage display
Highest Status Research
Template Name Ubiquitin
Protein Scaffold Information of This SBP
Scaffold ID PS005
Scaffold Info
[1]
Scaffold Name Affilin
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Beta-Turns + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fibronectin
BTS Info
Binder Tumors [ICD-11: XH1N44] Kd: 0.19 nM Scil Proteins GmbH(http://www.scilproteins.com/) [1]
References
1 Novel ubiquitin-derived high affinity binding proteins with tumor targeting properties. J Biol Chem. 2014 Mar 21;289(12):8493-507.