General Information of Synthetic Binding Protein (SBP) (ID: SBP000226)
SBP Name
Avimer anti-HGFR C426
Synonyms
Avimer C426
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS014
Scaffold Info
[1]
Scaffold Name Avimer
Scaffold Class Non-Antibody
Fold Type (Ca2+) + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Hepatocyte growth factor receptor
BTS Info
Inhibitor Research tool Kd: <0.1 nM Avidia [1]
References
1 Mult ivalent avimer proteins evolved by exon shuffling of a family of human receptor. Nat Biotechnol. 2005 Dec;23(12):1556-61.