Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000224)
SBP Name	Peptide aptamer anti-PSMA DUP-1
Synonyms	Peptide aptamer DUP-1
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS051 Scaffold Info					[1] , [2]
Scaffold Name	Peptide aptamer
Scaffold Class	Non-Antibody
Fold Type	Alpha-Helices + Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Glutamate carboxypeptidase 2	BTS Info	Binder	Tumors [ICD-11: XH1N44]; Diagnostic reagent	N.A.	University of Heidelberg	[1] , [2]

References

1	A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy. Clin Cancer Res. 2005 Jan 1;11(1):139-46.
2	Enhanced growth inhibition of prostate cancer in vitro and in vivo by a recombinant adenovirus-mediated dual-aptamer modified drug delivery system. Cancer Lett. 2016 Dec 28;383(2):230-242.