General Information of Synthetic Binding Protein (SBP) (ID: SBP000211)
SBP Name
Peptide aptamer anti-CaM SNP-D4
Synonyms
Peptide aptamer SNP-D4
Molecular Weight 18 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli XL1-Blue
Selection Method Bacterial two-hybrid system
Highest Status Research
SBP Sequence
>Inserted sequence
VTFLVNTYPNGVQSRA
3D Structure
Computationally Modelled Structure
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Template Name Staphylococcus aureus nuclease
Protein Scaffold Information of This SBP
Scaffold ID PS051
Scaffold Info
[1]
Scaffold Name Peptide aptamer
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Calmodulin
BTS Info
Inhibitor Rice blast Kd: 20000 nM Hainan University [1]
References
1 Engineering a peptide aptamer to target calmodulin for the inhibition of Magnaporthe oryzae. Fungal Biol. 2019 Jul;123(7):489-496.