Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000205)
SBP Name	Peptide aptamer anti-STAT5 S5-DBD-PA
Synonyms	Peptide aptamer S5-DBD-PA
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS051 Scaffold Info					[1]
Scaffold Name	Peptide aptamer
Scaffold Class	Non-Antibody
Fold Type	Alpha-Helices + Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Signal transducer and activator of transcription 5A	BTS Info	Inhibitor	Tumors [ICD-11: XH1N44]	N.A.	Georg-Speyer-Haus, Institute for Biomedical Research	[1]

References

1

The inhibition of stat5 by a Peptide aptamer ligand specific for the DNA binding domain prevents target gene transactivation and the growth of breast and prostate tumor cells. Pharmaceuticals (Basel). 2013 Aug 20;6(8):960-87.