Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000202)
SBP Name	Peptide aptamer anti-Hsp70 A8/17
Synonyms	Peptide aptamer A8/17
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS051 Scaffold Info					[1] , [2]
Scaffold Name	Peptide aptamer
Scaffold Class	Non-Antibody
Fold Type	Alpha-Helices + Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Heat shock 70 kDa protein 1A	BTS Info	Binder	Cancers [ICD-11: 2D4Z]	N.A.	INSERM UMR	[1] , [2]

References

1	Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy. Cancer Res. 2011 Jan 15;71(2):484-95.
2	Peptide aptamers with biological and therapeutic applications. Curr Med Chem. 2011;18(27):4215-22.