Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000126) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DARPin anti-HIV-1 5m3_D12
|
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| Synonyms |
DARPin 5m3_D12
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Ribosome display | |||||
| Highest Status | Research | |||||
| PDB ID | 5LW2 | |||||
| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS027 | [1] | ||||
| Scaffold Name | DARPin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Envelope glycoprotein gp160 | Modulator | Human immunodeficiency virus infection (HIV infection) [ICD-11: 1C62.Z] | N.A. | University of Zurich | [1] | |