General Information of Synthetic Binding Protein (SBP) (ID: SBP000091)
SBP Name
Anticalin anti-PQ clone 1
Synonyms
Anticalin PQ-1
Molecular Weight 17 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Selection Method Ribosome display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS011
Scaffold Info
[1]
Scaffold Name Anticalin
Scaffold Class Non-Antibody
Fold Type One Alpha-Helix + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Paraquat
BTS Info
Binder Research tool Kd: 72.2 nM Tianjin Medical University Cancer Institute and Hospital; Tianjin's Clinical Research Center for Cancer [1]
References
1 Selection of an artificial paraquat-specific binding protein from a ribosome display library based on a lipocalin scaffold. Biotechnol Appl Biochem. 2020 Nov 10.