Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003382) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv Licaminlimab
|
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| Synonyms |
Licaminlimab
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| Molecular Weight | 26.8 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Phase II | |||||
| Sequence Length | 253 | |||||
| SBP Sequence |
>scFv Licaminlimab
MEIVMTQSPSTLSASVGDRVIITCQSSQSVYGNIWMAWYQQKPGRAPKLLIYQASKLASG VPSRFSGSGSGAEFTLTISSLQPDDFATYYCQGNFNTGDRYAFGQGTKLTVLGGGGGSGG GGSGGGGSGGGGSEVQLVESGGSVQPGGSLRLSCTASGFTISRSYWICWVRQAPGKGLEW VGCIYGDNDITPLYANWAKGRFTISRDTSKNTVYLQMNSLRAEDTATYYCARLGYDFYAY DLWGQGTTVTVSS |
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| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor | Binder | Breast cancer [ICD-11: 2C6Z] | N.A. | Oculis | [1] | |