Details of the BTS
General Information of Binding Target of SBP (BTS) (ID: ST00609) | ||||||
---|---|---|---|---|---|---|
BTS Name |
Nectin cell adhesion molecule 4
|
|||||
BTS Type |
Protein
|
|||||
Family |
nectin family
|
|||||
Organism |
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
|
|||||
UniProt ID | ||||||
UniProt Entry | ||||||
PFam | ||||||
Sequence |
MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGE
QVGQVAWARADAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPS VTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHIL HVSFLAEASVRGLEDQNLWHVGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTL GFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQSEEPEGRSY STLTTVREIETQTELLSPGSGRTEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYING RGHLV |
|||||
Sequence Length |
485
|
|||||
Synthetic Binding Protein (SBP) Targeting This BTS |
---|
SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
---|---|---|---|---|---|---|
Bicyclic peptide BT7480 | Phase II | binder | Kd: 28 nM | Cancers [ICD-11: 2D4Z] | [1] | |