Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00608) | ||||||
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| BTS Name |
Nectin cell adhesion molecule 4
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| BTS Type |
Protein
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| Family |
nectin family
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| Gene Name |
Nectin4
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| Organism |
Rattus norvegicus (Rat)
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
MPLSLGAEMWGPEAWLLLLFLASFTGRYSAGELETSDLVTVVLGQDAKLPCFYRGDPDEQ
VGQVAWARVDPNEGTRELALLHSKYGLHVSPAYEDRVEQPPPPRDPLDGSILLRNAVQAD EGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSV TWDTEVKGTQSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHTLQ VAFLAEASVRGLEDQNLWHVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLG FPPLTTEHSGVYVCHVSNELSSRASQVTVEVLDPEDPGKQVDLVSASVVVVGVIAALLFC LLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEG HPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEEDDQDEGIKQAM NHFVQENGTLRAKPTGNAQTFAARIRRFSIQTLCGLKSAGLKEKLSFHPQVTQDLWTPRI WGLSVYISCKYMYICT |
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| Sequence Length |
556
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Bicyclic peptide BT7480 | Phase II | binder | Kd: 25 nM | Cancers [ICD-11: 2D4Z] | [1] | |