Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00604) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
Acetylcholine receptor, alpha-1-beta-1-gamma-deltanAChRs
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| BTS Type |
Protein
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| Family |
Alpha-1/CHRNA1 sub-subfamily;
Beta-1/CHRNB1 sub-subfamily; Gamma/CHRNG sub-subfamily |
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| Organism |
Tetronarce californica (Pacific electric ray) (Torpedo californica)
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| Synthetic Binding Protein (SBP) Targeting This BTS |
|---|
| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Knottin anti-nAChR Ms11a-1 | Research | Inhibitor | IC50: 408 nM | Tools for binding to distinct subtypes of nAChRs as well as to inhibit their function | [1] | |
| Knottin anti-nAChR Ms11a-2 | Research | Inhibitor | IC50: 1080 nM | Tools for binding to distinct subtypes of nAChRs as well as to inhibit their function | [1] | |
| Knottin anti-nAChR Ms11a-3 | Research | Inhibitor | IC50: 256 nM | Tools for binding to distinct subtypes of nAChRs as well as to inhibit their function | [1] | |
| Knottin anti-nAChR Ms11a-4 | Research | Inhibitor | IC50: 14950 nM | Tools for binding to distinct subtypes of nAChRs as well as to inhibit their function | [1] | |