General Information of Binding Target of SBP (BTS) (ID: ST00594)
BTS Name
Vacuolar protein sorting-associated protein 29-Vacuolar protein sorting-associated protein 35
Synonyms
Vps29-Vps35
BTS Type
Protein
Family
VPS29 family;
VPS35 family
Organism
Homo sapiens (Human)
UniProt ID
Q9UBQ0, Q96QK1
UniProt Entry
VPS29_HUMAN, VPS35_HUMAN
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Macrocyclic peptide anti-retromer RT-D1 Research Inhibitor Kd: 106 nM Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
SBP Info
[1]
Macrocyclic peptide anti-retromer RT-D2 Research Inhibitor Kd: 65 nM Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
SBP Info
[1]
Macrocyclic peptide anti-retromer RT-D3 Research Inhibitor Kd: 29 nM Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
SBP Info
[1]
Macrocyclic peptide anti-retromer RT-L1 Research Inhibitor Kd: 90 nM Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
SBP Info
[1]
Macrocyclic peptide anti-retromer RT-L2 Research Inhibitor Kd: 763 nM Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
SBP Info
[1]
References
1 De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Sci Adv. 2021 Dec 3;7(49):eabg4007.