General Information of Binding Target of SBP (BTS) (ID: ST00590)
BTS Name
Potassium voltage-gated channel subfamily H member 2/Integrin beta-1
Synonyms
hERG1/beta1
BTS Type
Protein
Family
potassium channel family. H (Eag) (TC 1.A.1.20) subfamily;
Kv11.1/KCNH2 sub-subfamily;
integrin beta chain family
Organism
Homo sapiens (Human)
UniProt ID
Q12809, B0FYY4
UniProt Entry
KCNH2_HUMAN, ITB1_SHEEP
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Diabody scDb-hERG1-beta1 Research binder N.A. Cancers [ICD-11: 2D4Z]
SBP Info
[1]
References
1 Harnessing the hERG1/1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers. Mol Cancer Ther. 2021 Aug;20(8):1338-1349.