Details of the BTS

General Information of Binding Target of SBP (BTS) (ID: ST00416)
BTS Name
Vascular endothelial growth factor 165
Synonyms
VEGF165
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Diabody anti-VEGF x anti-PD-1 Research Inhibitor Kd: 124.9 nM Tumors [ICD-11: XH1N44]
SBP Info
 		[1], [2]
References
1 Optimized Expression and Characterization of a Novel Fully Human Bispecific Single-Chain Diabody Targeting Vascular Endothelial Growth Factor165 and Programmed Death-1 in Pichia pastoris and Evaluation of Antitumor Activity In Vivo. Int J Mol Sci. 2018 Sep 25;19(10):2900.
2 Isolation and characterization of human anti-VEGF165 monoclonal antibody with anti-tumor efficacy from transgenic mice expressing human immunoglobulin loci. Cancer Lett. 2009 Jan 8;273(1):28-34.