Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00341) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
LIM domain-binding protein 1
|
|||||
| Synonyms |
LDB-1; xLdb1
|
|||||
| BTS Type |
Protein
|
|||||
| Family |
LDB family
|
|||||
| Gene Name |
ldb1
|
|||||
| Organism |
Xenopus laevis (African clawed frog)
|
|||||
| Function |
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. Acts as a coactivator together with otx2 to stimulate lhx1/lim1-mediated activation of the gsc promoter in the Spemann organizer. Acts synergistically with lhx1/lim1 and ssbp in axis formation.
|
|||||
| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRLQNWTEECDNLWWDAFTTE
FFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGGATELYYVLKHPKESFHNNFVS LDCDQCTMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIKTWHFSIRQHRELIPRSILAMH AQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTYSLSPRDCLKTCLFQ KWQRMVAPPAEPARQAPSKRRKRKMSGGSTMSSGGGNTNNSNSKKKSPASTFALSSQVPD VMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPPS SQESKSENPTSQASQ |
|||||
| Sequence Length |
375
|
|||||
| Synthetic Binding Protein (SBP) Targeting This BTS |
|---|
| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| DARPin anti-LDB1 clone 3 | Research | Binder | N.A. | Research tool | [1] | |